CAR T-Cell Therapy Evolution
Traditionally, solid tumors (kidney, ovarian, pancreatic) were thought to be “patchworks.” Scientists believed some cancer cells were “antigen-negative” (lacking the target protein), allowing them to hide from T-cells and cause a relapse. The Innovation: HIT Receptors To solve this, researchers developed HLA-independent T-cell (HIT) receptors. This is a significant shift in synthetic biology: Feature Conventional […]
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